Some clinicians have suggested that therapy should be initiated when serum urate concentrations exceed 9 mg/dL because these concentrations are often associated with increased joint changes and renal complications.
Allopurinol treatment of gout is directed at reducing uric acid production.
Because therapy with allopurinol is not without risks, the drug is not recommended for the management of asymptomatic hyperuricemia.
Allopurinol tablets can use to lower serum and urinary uric acid concentrations in the management of primary and secondary gout. The drug is indicated in patients with frequent disabling attacks of gout.